Please give me the answer to the A-level Biology Question How does Acetylcholine act on a neuronal synapse, and how is it re-uptaken?

Ca2+ voltage-gated channels are activated because of an action potential being able to reach the synapse
- Acetylcholine is found inside the cleft of pre-synaptic synaptic neurons
They are stored in vesicles
- the calcium-induced influx leads the vesicles of the brain to move and to join with the pre-synaptic membrane.
It is when they release the contents (Ach) to the synaptic cell via diffusion via a channel
Ach binds with neuroreceptors located in the post synaptic junction, which causes the channels to expand and depolarisation to take place within the postsynaptic cleft
- The excess Ach inside the synaptic gap is degraded by Acetylcholinesterase and subsequently result in Acetate and Choline
Choline is transported to the axon terminal where it is used to generate an increase in Ach inside the presynaptic neurons.


>>>>> Answered by a professional private A-level Biology Tutor >>>>> Do you need help to learn, study or revise? Check out our award-winning A-level Biology Tutors


Check out more A-level Biology questions and answers to help you study-

Describe how the lac operon works when lactose is both present and absent.
Describe the stages in DNA transcription and translation
Describe and explain how the lac Operon allows E coli bacteria to adapt to a new environment.
What is the difference between DNA and mRNA?
How do I answer questions on the adaptations of the lungs
Explain how action potentials are transmitted across synapses.
Explain how anti-diuretic hormone (ADH) is released and acts on cells in the collecting duct wall?
Could you explain the difference between passive diffusion and facilitated transport?
If the concentration of testosterone in a man’s blood starts to rise above normal, this system leads to a reduction in testosterone. How does this occur?


Karol Pysniak
Karol Pysniak

Richard Evans is the dynamic founder of The Profs, NatWest’s Great British Young Entrepreneur of The Year and Founder of The Profs - the multi-award-winning EdTech company (Education Investor’s EdTech Company of the Year 2024, Best Tutoring Company, 2017. The Telegraphs' Innovative SME Exporter of The Year, 2018). Sensing a gap in the booming tuition market, and thousands of distressed and disenchanted university students, The Profs works with only the most distinguished educators to deliver the highest-calibre tutorials, mentoring and course creation. The Profs has now branched out into EdTech (BitPaper), Global Online Tuition (Spires) and Education Consultancy (The Profs Consultancy).Currently, Richard is focusing his efforts on 'levelling-up' the UK's admissions system: providing additional educational mentoring programmes to underprivileged students to help them secure spots at the UK's very best universities, without the need for contextual offers, or leaving these students at higher risk of drop out.

Leave Message

Your email address will not be published. Required fields are marked *